![]() ![]() Peak flow rates can vary widely in asthmatic patients and often reach their nadir at night during sleep. In addition, there is a positive correlation between gastroesophageal reflux disease and OSA, and the presence of both disorders may exert a synergistic negative effect on nocturnal asthma.ĭiurnal variation in peak expiratory flow rates There is a positive association between OSA, snoring, a history of asthma, and common symptoms of asthma such as wheezing. In addition to increased symptoms at night and impaired sleep quality, there appears to be a significant relationship between obstructive sleep apnea and nocturnal asthma. Another study demonstrated asthmatics were twice as likely to complain of difficulty initiating sleep or early morning awakenings, and were 50% more likely to have symptoms of excessive daytime sleepiness. Turner-Warwick surveyed 7729 patients with asthma and found that 74% of respondents experience nocturnal cough and wheeze at least once a week, 64% complained of nocturnal awakenings with asthma symptoms at least three times per week, and 40% awaken nightly. The vast majority of asthmatics experience nocturnal symptoms at least once in their lifetimes and many suffer from them routinely. The interaction is reciprocal, as asthma can affect sleep quality and impact obstructive sleep apnea, but sleep-related physiological changes can also affect the clinical presentation of asthma. In addition, a significant and clinically relevant interaction between sleep and asthma has been demonstrated. This review will focus on the epidemiology, pathogenesis, and clinical implications of sleep disturbances in asthma and COPD, and briefly discuss the diagnostic evaluation and available therapies.Įpidemiology of Asthma and Sleep DisordersĪpproximately 14–20 million people in the United States have asthma. It has also been suggested that there may be a pathologic relationship between obstructive sleep apnea (OSA) and obstructive lung diseases. Sleep fragmentation and resultant sleep deprivation can lead to excessive daytime sleepiness and contribute to poor daytime cognitive function leading to social and mental problems. People with COPD and those with asthma have been shown to have worse sleep quality and more sleep-related problems when compared to people with other chronic health problems. It appears that there is also a correlation between sleep quality and the obstructive lung diseases. Strikingly, both asthmatic patients and COPD patients are more likely to die at night when compared to the general population. It is unclear why asthma and COPD worsen at night, but this may be due to circadian variations in pulmonary function, inflammation, secretion of hormones, and influences from other concomitant health problems such as gastroesophageal reflux disease. COPD patients often also have increased symptoms at night. Nocturnal asthma is associated with increases in symptoms, worsening of lung function, and increased morbidity. Nocturnal asthma is a variable exacerbation of the asthmatic condition occurring at night. It is estimated that 16 million people in the United States have COPD.Īsthma symptoms including cough, wheezing, chest tightness, and dyspnea often worsen at night. COPD is characterized by airway obstruction that is not fully reversible. Asthma affects over 14 million adults and 6 million children in the United States. ![]() Asthma is defined by reversible airway obstruction caused by inflammation of the lung’s airways, often as a response to various triggers. Asthma and chronic obstructive pulmonary disease (COPD) are the two most common forms of obstructive lung diseases. Obstructive lung diseases are characterized by a limitation of airflow when measured by spirometry. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |